Sunday, March 28, 2010

deodorant = alzheimer + cancer ??

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Deodorants are substances applied to the body to eliminate body odor caused by the bacterial breakdown of perspiration A subgroup of deodorants, antiperspirants, prevent odor and reduce sweat produced by parts of the body. Antiperspirants are typically applied to the underarms, while deodorants may also be used on feet and other areas in the form of body sprays.
A small percentage of people are
allergic to aluminium and may experience contact dermatitis when exposed to aluminium containing deodorants.

The use of aluminium-containing antiperspirants has been linked with the systemic accumulation of aluminium which increases the risk of Alzheimer's disease

Personal care products are a potential contributor to the body burden of aluminium and newer evidence has linked breast cancer with aluminium-based antiperspirants

Human perspiration is largely odorless until it is fermented by bacteria. Bacteria thrive in hot, humid environments. The human underarm is among the most consistently warm areas on the surface of the human body, and sweat glands provide moisture, which when excreted, has a vital cooling effect. When adult armpits are washed with alkaline pH soaps, the skin loses its acid mantel (pH 4.5 - 6), raising the skin pH and disrupting the skin barrier. Bacteria thrive in high pH or base environments. Creating such an environment in the armpit makes it more susceptible to bacterial colonization. The bacteria feed on the sweat from the apocrine glands and on dead skin and hair cells, releasing 3-methyl-2-hexenoic acid in their waste, which is the primary cause of body odor. Underarm hair wicks the moisture away from the skin and aids in keeping the skin dry enough to prevent or diminish bacterial colonization. The hair is less susceptible to bacterial growth and therefore is ideal for preventing the bacterial odor.
Deodorants are classified and regulated as over-the-counter medication (OTC) cosmetics by the
U.S. Food and Drug Administration(FDA) and are designed to eliminate odor. Deodorants are usually alcohol-based. Alcohol initially stimulates sweating, but may also temporarily kill bacteria. Deodorants can be formulated with other, more persistent antimicrobials such as triclosan, or with metal chelant compounds that slow bacterial growth. Deodorants may contain perfume fragrances or natural essential oils intended to mask the odor of perspiration.
Deodorants may be combined with antiperspirants — classified as drugs by the FDA — which attempt to stop or significantly reduce perspiration and thus reduce the moist climate in which bacteria thrive.
Aluminium chloride, aluminium chlorohydrate, and aluminium-zirconium compounds, most notably aluminium zirconium tetrachlorohydrex gly and aluminium zirconium trichlorohydrex gly, are frequently used in antiperspirants. Aluminium-based complexes react with the electrolytes in the sweat to form a gel plug in the duct of the sweat gland. The plugs prevent the gland from excreting liquid and are removed over time by the natural sloughing of the skin. The metal salts work in another way to prevent sweat from reaching the surface of the skin: the aluminum salts interact with the keratin fibrils in the sweat ducts and form a physical plug that prevents sweat from reaching the skin’s surface. Aluminum salts also have a slight astringent effect on the pores; causing them to contract, further preventing sweat from reaching the surface of the skin. The blockage of a large number of sweat glands reduces the amount of sweat produced in the underarms, though this may vary from person to person.
Aluminium chlorohydrate and aluminium zirkonium tetrachlorohydrate glycine complex are the most frequent active ingredients in commercial
antiperspirants.A popular alternative to modern commercial deodorants is ammonium alum, which is a common type of alum sold in crystal form and often referred to as a deodorant crystal. It has been used as a deodorant throughout history in Thailand, the Far East, Mexico and other countries.
Deodorants and antiperspirants come in many forms. What is commonly used varies in different countries. In Europe,
aerosol sprays are popular, as are cream and roll-on forms. In the United States, solid or gel forms are dominant

it can cause to:

Breast Cancer
A 2003 by the European Journal of Cancer Prevention, found a correlation between earlier diagnosis of breast cancer and antiperspirant/deodorant use.A 2004 study reviewing the evidence for and against the possible link between breast cancer and underarm cosmetics said "Although animal and laboratory studies suggest a possible link between certain chemicals used in underarm cosmetics and breast cancer development, there is no reliable evidence that underarm cosmetics use increases breast cancer risk in humans.Researcher Dr. Phil Darbre, hypothesizes that particular substances in deodorants, such as preservatives called parabens, or bolts such as aluminum chloride used in antiperspirants, get into the bloodstream or accumulate in breast tissue, where they enhance or emulate the effects of estrogen, which stimulates the growth of cancerous breast cells In 2003, the European Journal of Cancer Prevention stated "underarm shaving with antiperspirant/deodorant use may play a role in breast cancer." In 2009, the journal The Breast Cancer Research proposed a link between breast cancer and the application of cosmetic chemicals in the underarm, including aluminum, with oestrogenic and/or genotoxic properties.A 2007 study found that personal care products are a potential contributor to the body burden of aluminium and newer evidence has linked breast cancer with aluminium-based antiperspirants


One of the suspected environmental risks for the development of Alzheimer’s disease, which has been highly controversial in the scientific literature, is lifelong exposure to high levels of aluminum. Exposure may come through many sources, including drinking water, cooking with aluminum pots and pans and use of antiperspirants. Most antiperspirants contain aluminum salts, and there is a potential risk that aluminum may be absorbed through the skin of the armpit, resulting in ultimate accumulation of high levels of this metal in the brain.
Studies of brain tissue in the test tube or in animals have shown that aluminum in high concentrations can be toxic to nerve cells. This type of research, which is many steps away from the true human condition, has been supported by comparisons of brains from patients who have passed away from Alzheimer’s disease to those of individuals who have died from other conditions.
Specifically, aluminum levels were found to be higher in Alzheimer’s brains than in non-Alzheimer’s brains. However, many large studies of populations exposed to drinking water containing high and low levels of aluminum have demonstrated inconsistent results and were inconclusive in proving aluminum as an independent risk factor for the development of Alzheimer’s disease.
The Canadian Study of Health and Aging did not demonstrate a link between antiperspirant use and risk for developing Alzheimer’s disease. Currently, there is no strong scientific basis to support the premise that aluminum, in the particular form contained in antiperspirants, can cause or increase risk of Alzheimer’s disease.